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Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
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机译:制备悬浮气雾剂的方法,其中颗粒是通过气雾罐内的沉淀形成的
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摘要
The present invention provides processes for preparing suspension aerosol formulations, wherein the particles for inhalation are formed in situ during the process of manufacturing the formulation. In one aspect of the invention, a process for preparing a suspension aerosol formulation comprises the steps of:(a) dissolving one or more medicaments in one or more solvents to form a solution; and(b) mixing one or more propellants with the solution under conditions effective to precipitate, entirely or partially, at least one of the medicaments.
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