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Flow assessment apparatus and method for quantitatively assessing the flow properties of particulate material

机译:用于定量评估颗粒材料的流动特性的流量评估设备和方法

摘要

A flow assessment apparatus 10 is provided for quantitatively assessing the flow properties of particulate material, such as pharmaceutical formulations and constituent powders. The apparatus 10 includes a vibratory feed device 12 having an inclined dispensing member 16. Particulate material is induced to flow along the inclined member 16 onto a watch glass 18 positioned on a top pan balance 20. The mass of material dispensed onto the watch glass 18 is recorded over a given time period, for example a set time period of 1 minute, or a visually assessed time period where it is deemed that sufficient material has been dispensed. The mass and time data is used to calculate a value representative of a relative flow property of the material, which can be used in the development of pharmaceutical formulations.
机译:提供了一种流动评估设备10,用于定量地评估诸如药物制剂和成分粉末的颗粒材料的流动特性。设备10包括具有倾斜的分配构件16的振动进给装置12。使颗粒状的材料沿倾斜的构件16流动到位于顶部秤盘20上的手表玻璃18上。物料的质量被分配到手表玻璃18上。在给定的时间段内(例如1分钟的设定时间段)或可视化评估的时间段(被认为已分配了足够的物料)记录了记录值。质量和时间数据用于计算代表材料相对流动性的值,该值可用于药物制剂的开发。

著录项

  • 公开/公告号EP1977737A1

    专利类型

  • 公开/公告日2008-10-08

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号EP20070251520

  • 发明设计人 THAKUR ARUN A.C/O WYETH RESEARCH;

    申请日2007-04-05

  • 分类号A61K9/20;G01G13/02;G01N11/04;

  • 国家 EP

  • 入库时间 2022-08-21 19:55:05

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