Degradable linear Polyethylenimine-co-Polyether Copolymers as a Novel Gene Carrier

摘要

The present invention relates to a gene carrier to a copolymer of biodegradable polyethylenimine and polyether as a main constituent. Gene carrier of the present invention, the gene transfer efficiency is high, but a high gene delivery systems that can be substituted for the PEI 25K that has a limitation in practical application because of its cell toxicity and its role is expected, as well as his This biodegradability and low cytotoxicity, high it is expected that the possibility of applying very high as a safe gene delivery due to the gene transfer efficiency.; Gene delivery system, biodegradable, polyethylenimine, polyether