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Terpyridine derivatives, manufacturing process thereof and anticancer composition containing them

机译:联吡啶衍生物,其制备方法和含有它们的抗癌组合物

摘要

PURPOSE: Provided are terpyridine derivatives, a manufacturing process thereof and an anticancer composition containing them. The anticancer agent has excellent anticancer activity, high selectivity to cancer cells and reduced adverse effects. CONSTITUTION: The terpyridine derivative is represented by the formula(1), wherein A is a radical represented by the formula(2), (3) or (4); B is a radical represented by the formula(2), (3) or (4); and C is a radical represented by the formula(2), (3), (4), (5), (6), (7) (8) or (9). It is manufactured by the reaction of a compound of the formula(13) and a compound of the formula(14) in the presence of ammonium acetate.
机译:用途:提供了联吡啶衍生物,其制备方法和包含它们的抗癌组合物。该抗癌剂具有优异的抗癌活性,对癌细胞具有高选择性并减少了不良反应。组成:三联吡啶衍生物由式(1)表示,其中A是由式(2),(3)或(4)表示的基团; B是由式(2),(3)或(4)表示的基团; C为由式(2),(3),(4),(5),(6),(7),(8)或(9)表示的基团。它是由式(13)的化合物与式(14)的化合物在乙酸铵存在下反应制备的。

著录项

  • 公开/公告号KR100851608B1

    专利类型

  • 公开/公告日2008-08-12

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20010047620

  • 申请日2001-08-08

  • 分类号C07D409/14;

  • 国家 KR

  • 入库时间 2022-08-21 19:51:48

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