NEW ASSOCIATION BETWEEN AGOMELATINE AND A NORADRENALINE REUPTAKE INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

摘要

Association (I) of agomelatine (N-[2-(7-methoxy-1-naphthyl) ethyl]acetamide) and an agent inhibiting noradrenalin recapture or permitting the increase of noradrenalin concentration at the extracellular level. ACTIVITY : Antidepressant; Neuroleptic; Tranquilizer; Hypnotic. MECHANISM OF ACTION : Melatoninergic receptor system agonist; 5-Hydroxytryptamine receptor antagonist.