METHODS FOR ANALYSIS OF TISSUE INFLAMMATORY RESPONSE USING PROFILES OF GENE EXPRESSION IN ENDOTHELIAL CELLS

摘要

The invention provides methods of assessing a tissue inflammatory response, comprising making a quantitative determination of the level of at least five transcripts shown in Table 1, or proteins encoded thereby, in a sample; and comparing the abundance of said transcripts or proteins so determined with the level of said transcript obtained from a control sample. Methods for diagnosis of a condition with which a tissue inflammatory response is associated are also provided, as are gene chip arrays and protein based assays suitable for use in these methods. Assay methods for determining a modulator of a tissue inflammatory response or a condition associated therewith also form part of the invention.