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Pharmaceutical compositions having neuroprotective, antiamnestic, antihypoxic and antiischemic activity and methods of making a pharmaceutical composition

机译:具有神经保护,抗记忆删除,抗缺氧和抗缺血活性的药物组合物及其制备方法

摘要

1. A pharmaceutical composition having neurotrophic, antiamnestic, antihypoxic and antiischemic activity, characterized in that as active component contains semaks and meksidol or their pharmaceutically acceptable salts in therapeutically effective kolichestvah.2. A pharmaceutical composition according to claim 1, characterized in that made in lyophilized forme.3. A pharmaceutical composition according to claim 1, further comprising a pH adjusting agent and vodu.4. A pharmaceutical composition according to claim 3, characterized in that the pH regulator substance use of ammonium acetate in the following ratio, r: 0.4-5.0 meksidol; semaks 0,0001-0,03; 0.71 ammonium acetate; 1 M acetic acid to pH 4.5-5.5, and water for injection to 1 l.5. A process for preparing a pharmaceutical composition according to claim 1, characterized in that the active ingredients or their pharmaceutically acceptable salts are dissolved in purified water and the resulting solution was lyophilized.
机译:1,一种具有神经营养,抗记忆删除,抗缺氧和抗缺血活性的药物组合物,其特征在于作为有效成分,在治疗有效的科利司他韦中含有semaks和meksidol或其药学上可接受的盐。 2.根据权利要求1所述的药物组合物,其特征在于,所述药物组合物以冻干的形式制备。 2.根据权利要求1的药物组合物,进一步包含pH调节剂和vodu.4。 4.根据权利要求3所述的药物组合物,其特征在于,所述pH调节剂物质以下列比例使用乙酸铵,r:0.4-5.0甲磺吡啶;信号0,0001-0,03; 0.71醋酸铵; 1 M乙酸至pH 4.5-5.5,注射用水至1 l.5。 2.根据权利要求1的药物组合物的制备方法,其特征在于将活性成分或其药学上可接受的盐溶于纯净水中,并将所得溶液冻干。

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