BUTORPHANOL-BASE INJECTION SOLUTION POSSESSING ANALGESIC EFFECT

摘要

FIELD: medicine, pharmacy.;SUBSTANCE: invention proposes an injection solution comprising the following components, wt.-%: butorphanol tartrate, 0.05-0.5; stabilizing agent, 1.6-5.4; chelating agent, 0.001-5.0, and water for injection, the balance. Invention provides decreasing concentration of active substance in preparing the equal pharmacological effect as compared with nalbuphine solution that allows reducing hazard effect of analgesic preparation on the body. The injection solution satisfies the quality index norm values for fitness period -3 years, not less.;EFFECT: improved and valuable medicinal and pharmaceutical properties of solution.;6 cl, 9 ex