METHOD FOR TREATING HYPERPLASTIC ENDOMETRIAL PROCESSES COMBINED WITH UTERINE MYOMA

摘要

FIELD: medicine, gynecology.;SUBSTANCE: additionally to histological inspection of endometrial scrapes off in which one should detect quantitative content and density of distributing the receptors of sex steroid hormones it is necessary to calculate the percentage and density in distributing estrogen-induced protein-PS₂. In case of low content of sex hormones receptors and, simultaneously, at low or negative PS₂ value one should carry out radical surgical therapy or endometrial ablation; in case of inflammatory process and at low or negative content of receptors against sex hormones, but at positive PS₂ value one should carry out preliminary antiphlogistic therapy, after it - hormonotherapy; at normal and high content of sex hormones receptors and positive P8₃ it is important to specify the size and the character of myomatous nodes and at diameter being under 3 cm (except submucosal myomas) one should carry out hormonotherapy, in case of single nodes at diameter ranged 3-5 cm and submucosal myomas one should carry out conservative myomectomy followed by hormonotherapy, and at the diameter of myomatous nodes being above 5 cm and/or in case of multiple myomas it is necessary to prescribe a certain technique and conservative myomectomy followed by the course of hormonotherapy. The innovation provides the chance for pathogenetically grounded individual approach to a patient and the choice of optimal therapeutic techniques due to taking into consideration the peculiarities of its hormonal receptor background.;EFFECT: higher efficiency of therapy.;2 cl, 4 ex, 1 tbl