METHOD FOR PRECLINICAL DIAGNOSTICS OF PARKINSON'S DISEASE IN PRACTICALLY HEALTHY PERSONS

摘要

FIELD: medicine.;SUBSTANCE: the present innovation deals with carrying out a prevocational test, moreover, it is necessary to introduce pharmacological preparation into blood of a person under testing followed by detecting body reaction to its action, moreover, as the above-mentioned pharmacological preparation one should introduce reversible inhibitor of catecholamines α-methyl-p-tyrosine synthesis, then visually detect the presence/absence of tremor and/or muscular rigidity in a person under testing, at the presence of which it is possible to diagnose pathological process in its latent phase of flow. The innovation enables to establish the diagnosis long before the manifestation of clinical symptoms and enables to apply adequate methods of therapy due to using the so-called prevocational pharmacological test that helps to clinically illustrate functional insufficiency of nigrostriatal dopaminergic cerebral system being responsible for the regulation of motor behavior.;EFFECT: higher accuracy of diagnostics.