NEW HETERO-AROMATIC INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHOTASE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHOD OF INHIBITING FRUCTOSE-1,6-BISPHOSPHOTASE

摘要

FIELD: chemistry.;SUBSTANCE: description is given of a hetero-aromatic compounds with a phosphonate group with formula (I) and their pharmaceutical salts, radicals of which are given in the formula of invention. The compounds are inhibitors of fructose-1,6-bisphosphotase. Description is also given of pharmaceutical compositions based on compounds with formula (I) and (X) and the method if inhibiting fructose-1,6-bisphosphotase, using the compound with formula (I).;EFFECT: obtaining of new biologically active substances.;184 cl, 52 tbl, 62 ex