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NANOCOMPOSITE PHOTOSENSITISER FOR METHOD OF PHOTODYNAMIC CELL EFFECT

机译:用于光细胞效应的纳米复合光敏剂

摘要

FIELD: medicine.;SUBSTANCE: invention can be used for photodynamic therapy method (PDT) of oncology diseases. As nanocomposite photosensitiser, powder consisting of porous silicon particles, including silicon crystals of sizes 2 to 4 nm with fullerene molecules adsorbed on crystal surface (e.g., C60 or C70) is offered, at relative fullerene in nanocomposite 0.3% to 4% by mass. The powder can be used in PTD, as, e.g. aqueous or saline suspension.;EFFECT: photosensitiser is high-effective to generate singlet oxygen, stable to water solutions aggregation, nontoxic for organism.;5 cl, 1 dwg
机译:技术领域:本发明可用于肿瘤疾病的光动力疗法(PDT)。作为纳米复合光敏剂,由多孔硅颗粒组成的粉末,包括大小为2-4 nm的硅晶体,富勒烯分子吸附在晶体表面(例如C 60 或C 70 )提供相对于富勒烯的纳米复合材料为0.3质量%至4质量%。该粉末可用于PTD中,例如。效果:光敏剂高效产生单线态氧,对水溶液聚集稳定,对生物无毒; 5 cl,1 dwg

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