首页> 外国专利> METHOD OF OBTAINING OF BIOLOGICALLY ACTIVE LIPID FRACTION OF SIBERIAN FIR (ABIES SIBIRICA) WOOD GREEN EXTRACT

METHOD OF OBTAINING OF BIOLOGICALLY ACTIVE LIPID FRACTION OF SIBERIAN FIR (ABIES SIBIRICA) WOOD GREEN EXTRACT

机译:西伯利亚冷杉木材绿色提取物生物活性油脂馏分的获得方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention is referred to pharmaceutical industry, in particular, to a method of obtaining of biologically active lipid fraction of a fir Siberian (Abies Sibirica) wood green extract. The method of obtaining of biologically active lipid fraction of a fir Siberian (Abies Sibirica) wood green extract, including extraction of dry crushed raw materials under certain conditions, washing by a solution of the alkaline agent, separation of layers into organic and water-alkaline phases. Extract an extracting agent from an organic phase under certain conditions with obtaining of lipid fraction; treat the water-alkaline layer with acid, separate the creating organic phase and obtain the amount of triterpene acids. Further accumulate lipid fraction of an extract, hydrolyse it with water, remove volatiles and obtain partially hydrolysed lipid fraction; further process partially hydrolysed lipid fraction with the aqueous-alcoholic alkali while boiling, concentrate using stripping, extract two times, dry up the extract, filter the dehydrating agent, concentrate the solution and obtain perhydrolysed lipid fraction.;EFFECT: obtaining of effective biologically active lipid fraction using simplified technology.;2 tbl, 4 ex
机译:技术领域:本发明涉及制药工业,尤其涉及一种获得西伯利亚冷杉(Abies Sibirica)木绿色提取物的生物活性脂质级分的方法。一种获得西伯利亚冷杉(Abies Sibirica)木材绿色提取物的生物活性脂质馏分的方法,包括在一定条件下提取干燥的粉碎原料,用碱性试剂溶液洗涤,将层分离为有机和水碱性阶段。在一定条件下,从有机相中提取萃取剂并获得脂质部分;用酸处理水-碱性层,分离产生的有机相并获得一定量的三萜烯酸。进一步积聚提取物的脂质级分,用水将其水解,除去挥发物,获得部分水解的脂质级分;进一步用沸腾的水-醇碱进一步处理部分水解的脂质馏分,通过汽提浓缩,萃取两次,将提取液干燥,过滤脱水剂,浓缩溶液,得到过水解的脂质馏分。效果:获得有效的生物活性使用简化技术的脂质分数。; 2 tbl,4 ex

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