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TOOLS FOR MODELLING experimental renal hypertension

机译:用于建模实验性肾脏高血压的工具

摘要

The invention relates to the field of biomedicine, namely the experimental physiology, and may be used for simulating renal hypertension in small animals (rats, mice). The object of the invention is to provide a device for modeling experimental renal hypertension small animals with individual approach. This is achieved by a qualitative change of clips to the construction described in the prototype and analogues. The technical result is to simplify the design while providing the possibility of taking into account the age factor (animal weight) and technical and methodological procedure of the operation for developing an experimental renal hypertension. The stated object is achieved in that the device for modeling experimental renal hypertension small animals, comprising a clip for clamping the renal arteries, according to the decision, a clip made of a metal strip having a bend that separates it into unequal parts, a large part has a bend for securing to a lesser part in the compressed state, the device is provided with a measuring probe in the form of a flat plate for installing the clip with a gap between the parts selected depending on the weight of dormancy ence of animals in the range of from 0.16 to 0.3 mm, and the length of the smaller part is selected from the conditions of simultaneous placement thereon of a flat plate and renal arteries. The clip is made of aluminum coated with a layer of inert material. The width of the clip is 1/5 the length of the renal artery. PF 3, 2 FIG.
机译:本发明涉及生物医学领域,即实验生理学,可用于模拟小动物(大鼠,小鼠)的肾性高血压。发明内容本发明的目的是提供一种通过个体方法对实验性肾性高血压小动物建模的装置。这是通过对原型和类似物中描述的结构的夹子进行定性改变来实现的。技术结果是简化设计,同时提供了考虑年龄因素(动物体重)以及发展实验性肾性高血压的手术技术方法的可能性。所述目的通过以下方式得以实现,即,用于对实验性肾高血压小动物进行建模的装置,包括用于夹紧肾动脉的夹子,根据该决定,该夹子由金属带制成,该金属带具有将其分成不相等部分的弯曲,该部件具有用于在压缩状态下固定至较小部件的弯曲部,该装置设有平板形式的测量探针,用于安装夹子,部件之间的间隙取决于动物的休眠重量而选择在0.16至0.3mm的范围内,小部分的长度是从平板和肾动脉同时放置的条件中选择的。夹子由涂有惰性材料层的铝制成。夹子的宽度是肾动脉长度的1/5。 PF 3,2图。

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