Topical dermatological preparations, for cosmetic or medicinal use, e.g. in moisturizing skin, contain active agent stored in multilamellar layers of hydrogenated liposomes

摘要

New topically active dermatological preparations (I) contain (a) 5-50 (preferably 20-40) wt. % hydrogenated liposomes; (b) 0.5-50 (preferably 0.5-40) wt. % active agent(s), stored in the multilamellar layers of the hydrogenated liposomes (a); and (c) water, solubilizers and cosmetic auxiliaries and supplementary components to a total of 100 %. An independent claim is included for the production of topically active dermatological preparations (I), in which the active agent is stored in the multilamellar layers of hydrogenated liposomes, by (i) mixing the hydrogenated liposomes, active agent and optionally water and auxiliaries at 90-110[deg] C and (ii) homogenizing the mixture under high pressure.