Combination for preparing medicine product for treatment of osteoporosis, prophylaxis or bone fractures, or for anchorage of implants, comprises calcium-containing substance and cross linking agent

摘要

The combination comprises collagen, an additional peptide comprising two reactive amino groups or hydroxyl groups. A calcium-containing substance and a cross linking agent with a terminally functionalized oligolactone, particularly ethylene glycol oligolactone, are provided. The calcium-containing substance is hydroxyl apatite. The oligolactone has terminal isocyanate groups. An independent claim is also included for a method for in vitro production of artificial bones, bone parts, implants or implant coatings. ACTIVITY : Osteopathic. MECHANISM OF ACTION : Collagen interlacing stimulator.