Fiber-tangled structure useful as cell settling material, wound covering, medical implant and carriers for pharmaceutical active substance and for producing depot medicament, comprises fibers made of partially interlaced gelatin material

摘要

The fiber-tangled structure useful as a cell settling material, a wound covering, a medical implant, a starting food product and carriers for a pharmaceutical active substance and for the production a depot medicament, comprises fibers made of partially interlaced gelatin material. The thickness of the fibers is 5-100 mu m. The tangled structure has areas, at which two or more fibers are turned into one another without phase boundary. The capillary suction effect of the tangled structure produces a capillary rise of = 15 respect to pure water in 120 seconds. The fiber-tangled structure useful as a cell settling material, a wound covering, a medical implant, a starting food product and carriers for a pharmaceutical active substance and for the production a depot medicament, comprises fibers made of partially interlaced gelatin material. The thickness of the fibers is 5-100 mu m. The tangled structure has areas, at which two or more fibers are turned to one another without phase boundary. The capillary suction effect of the tangled structure produces a capillary rise of = 15 respect to pure water in 120 seconds. The water absorbing capacity of the tangled structure is ten-fold or more of its dry weight. The gelatin material of = 60 wt.% is amorphous. The tangled structure has an initial wettability of = 1 with respect to pure water, a surface energy of = 10 mN/m, a tear resistance of 140-180 g/m 2 in the dry condition of = 0.15 N/mm 2, an elongation at tear of = 200%, and an open porous structure with an air permeability of = 0.5 l/minute cm 2. The tangled structure in hydrated condition forms a closed-porous, fibrous gel structure and has fiber fractions with different average fiber thickness. The fibers are produced by a rotor-spinning procedure and a part of the fibers has a twisted structure. The gelatin material has a gelatin of = 200 bloom. The tangled structure comprises further fibers, which are formed further material different from the gel material. The gel material has a pharmaceutical active substance. Independent claims are included for: (1) a surface material with layers; and (2) a procedure for the production of fiber tangled structure.