首页> 外国专利> HEMATOPOIETIC, MARKET-PROOFING, ANTITUMOR IMMUNOCELL-PRODUCING AND RADIOSENSIBILIZING POLYSACCHARIDE FROM PANAX GINSENG

HEMATOPOIETIC, MARKET-PROOFING, ANTITUMOR IMMUNOCELL-PRODUCING AND RADIOSENSIBILIZING POLYSACCHARIDE FROM PANAX GINSENG

机译:人参中的造血,防菌,抗免疫球蛋白和放射增敏多糖

摘要

The present invention relates to a polysaccharide composition having the hematopoietic, myeloprotecting, antitumor immune cell generating, and radiosensitizing activities extracted from the roots of Panax ginseng prepared by the steps of:i) obtaining the residue by extracting 1 wt part of ginseng roots with 2~4 wt part of methanol;ii) extracting and obtaining the water soluble fraction from the residue in step i) using 3~5 wt part of distilled water;iii) freeze-drying the obtained water soluble fraction in step ii);iv) obtaining the inner fraction using the dialysis membrane after obtaining the insoluble fraction to the 40% of ethanol from freeze-dried fraction in step iii);v) obtaining the 6 fractions by sephacryl S-500 gel chromatography; andvi) purifying the polysaccharide by DEAE-sephadex A-50 chromatography.
机译:本发明涉及从人参的根中提取的具有造血,骨髓保护,抗肿瘤免疫细胞生成和放射增敏活性的多糖组合物,其通过以下步骤制备:i)通过提取1重量份的人参根和2来获得残渣。 〜4重量份的甲醇; ii)在步骤i)中使用3〜5重量份的蒸馏水从残余物中提取并获得水溶性级分; iii)将在步骤ii)中获得的水溶性级分冷冻干燥;在步骤iii)中从冷冻干燥的级分获得对40%乙醇不溶的级分之后,使用透析膜获得内部级分; v)通过sephacryl S-500凝胶色谱法获得6个级分; vi)通过DEAE-sephadex A-50色谱法纯化多糖。

著录项

  • 公开/公告号DE60035406T2

    专利类型

  • 公开/公告日2008-04-17

    原文格式PDF

  • 申请/专利权人 KOREA ATOMIC ENERGY RESEARCH INSTITUTE;

    申请/专利号DE2000635406T

  • 发明设计人

    申请日2000-08-25

  • 分类号C12P19/04;A61K36;

  • 国家 DE

  • 入库时间 2022-08-21 19:48:35

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