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in breast and bladder cancer differentiell exprimiertes gene and the encoded polypeptide

机译:乳腺癌和膀胱癌差异基因的表达及其编码的多肽

摘要

The present invention relates to a novel human gene that is differentially expressed in human carcinoma. More specifically, the present invention relates to methods of treating or preventing a disorder in a subject. The invention further relates to uses of C35 polypeptides in immunogenic compositions or vaccines, to induce antibody or T cell-mediated immunity against target cells, such as tumor cells, that express the C35 gene. The present invention further relates to use of C35 polypeptides in diagnosing a pathological condition or susceptibility to a pathological condition in a subject.
机译:本发明涉及在人类癌中差异表达的新型人类基因。更具体地,本发明涉及治疗或预防受试者的疾病的方法。本发明进一步涉及C35多肽在免疫原性组合物或疫苗中用于诱导针对表达C35基因的靶细胞例如肿瘤细胞的抗体或T细胞介导的免疫的用途。本发明进一步涉及C35多肽在诊断受试者的病理状况或对病理状况的敏感性中的用途。

著录项

  • 公开/公告号DE60135315D1

    专利类型

  • 公开/公告日2008-09-25

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF ROCHESTER;

    申请/专利号DE20016035315T

  • 申请日2001-04-04

  • 分类号C12N15/09;C12N15/12;A61K31/7088;A61K35/76;A61K38;A61K39/395;A61K48;A61P35;A61P43;C07K14/47;C07K14/82;C07K16/30;C07K16/32;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12Q1/02;C12Q1/68;G01N33/50;

  • 国家 DE

  • 入库时间 2022-08-21 19:48:23

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