(6- (PHENOXY) -PYRIDOi3,4-DOPYRIMIDIN-2-YL) AMINE DERIVATIVES AS P38 KINASE INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS

摘要

Compounds having the formula (I) or (II), are useful as p38 kinase inhibitors, wherein R is an optionally substituted alkyl, cycloalkyl, or aryl; RSUP6 /SUPis hydrogen or lower alkyl; RSUP7 /SUPis hydrogen or a non-interfering substituent, and Q is a non-aromatic moiety as defined in the specification.