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mikrokanalreihenkomponente, mikrokanalreihen for recovery of biomolecules and method for recovery of biomolecules

机译:mikrokanalreihenkomponente,mikrokanalreihen用于生物分子的回收以及生物分子的回收方法

摘要

PROBLEM TO BE SOLVED: To readily recover various kinds of minute biomolecules to be recovered contained in a sample solution by separating these biomolecules according to dimension of affinity for various probe molecules.;SOLUTION: A sample solution 8 containing biomolecules 7 to be recovered is poured into a microchannel array 6. After the biomolecules 7 are bound to probe molecules which are fixed on the wall of a microchannel in the form of spots and which have a high affinity for the biomolecules 7, a second substrate having periodic protrusions is removed from the microchannel array 6. A portion of the microchannel array 6 that includes a spot in which the probe molecules that are bound to the biomolecules 7, which are the objects to be recovered for the first substrate, are fixed is cut with a sharp cutting knife, for example, thereby obtaining a piece that retains on the surface the probe molecules that are bound to the biomolecules 7.;COPYRIGHT: (C)2005,JPO&NCIPI
机译:解决的问题:通过根据对各种探针分子的亲和力大小分离这些生物分子,以便容易地回收样品溶液中所包含的各种微小的待回收生物分子;解决方案:倒入含有要回收的生物分子7的样品溶液8进入微通道阵列6。在将生物分子7结合至以斑点形式固定在微通道壁上并且对生物分子7具有高亲和力的探针分子之后,从该分子上除去具有周期性突起的第二底物。微通道阵列6。微通道阵列6的一部分包括一个点,在该点上,用锋利的切割刀切割与生物分子7结合的探针分子,该探针分子是第一基板的待回收对象。例如,从而获得一块在表面上保留与生物分子7结合的探针分子的部件。版权所有:(C)2005,JPO&NCIPI

著录项

  • 公开/公告号DE602004010037D1

    专利类型

  • 公开/公告日2007-12-27

    原文格式PDF

  • 申请/专利权人 HITACHI SOFTWARE ENGINEERING CO. LTD.;

    申请/专利号DE20046010037T

  • 发明设计人 KOGI OSAMU;

    申请日2004-09-15

  • 分类号B01L3/00;G01N33/53;B01J19/00;C12M1/00;C12N15/09;C40B50/14;G01N1/00;G01N1/04;G01N1/28;G01N35/00;

  • 国家 DE

  • 入库时间 2022-08-21 19:48:16

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