potent ganoderma lucidum spores for the treatment of systemic lupus erytrhomatosus (sle)

摘要

Germinated-activated Ganoderma lucidum spores are useful in the manufacture of medicament for treating immunological disorder in mammals. An independent claim is also included for a systemic lupus erythematosus agent, contains the germinated-activated Ganoderma lucidum spores. ACTIVITY : Immunosuppressive; Antiinflammatory; Dermatological. NIH small white mice (6-8 weeks old) were orally administered with 0.60 g/kg body weight of Ganoderma lucidum spores 10 times a day for 4 weeks. A control was similarly performed with cold distilled water. 4 days before the end of the test the animals were intraperitoneally injected with 0.2 ml of sheep erythrocytes and 4 days after the test the animals were subcutaneously injected with sheep erythrocytes. The results showed that administration of Ganoderma lucidum spores delayed allergic reactions in test group (standard deviation of thickness of foot pad was 0.68+-0.10), than the control (standard deviation of thickness of foot pad was 0.43+-0.16). The results indicated that G.lucidum spores had significant effective in delaying allergic reactions. MECHANISM OF ACTION : None given.