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conjugates of tc complex and targeted units and their use in nmr diagnosis
conjugates of tc complex and targeted units and their use in nmr diagnosis
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机译:tc复合物和目标单元的结合物及其在核磁共振诊断中的应用
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摘要
The present invention relates to improved 99mTc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed.
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