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Antibody molecules that specifically interact with the active site or active site of a target molecule
Antibody molecules that specifically interact with the active site or active site of a target molecule
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机译:与目标分子的一个或多个活性位点特异性相互作用的抗体分子
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摘要
The invention relates to a recognition molecule, being capable of interacting with an active site or cleft of a target molecule, which recognition molecule comprises an exposed loop structure, which extends from a basic recognition unit. The loop structure is for example the CDR3 of a camelid species heavy chain antibody having a binding specificity fo the active site or cleft of a target molecule, or a derived version of such a CDR3. The basic recognition unit is for example formed by an antibody-type structure having binding affinity for the target molecule.
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