MELANOSOME TRANSPORT INHIBITOR, AND SKINCARE PREPARATION FOR EXTERNAL USE CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a melanosome transport inhibitor, and to provide a skincare preparation for external use exhibiting melanosome transport inhibitory ability.;SOLUTION: The melanosome transport inhibitor is characterized by comprising coumarinic acid or a salt thereof as the active ingredient. The skincare preparation for external use contains coumarinic acid or a salt thereof as the active ingredient, and is characterized by having the effect of reducing the level of at least one protein among melanosome tranport-related proteins Rab27a and Slp2-a and myosin 5a in the skin.;COPYRIGHT: (C)2009,JPO&INPIT