POLYPEPTIDE DERIVED FROM HELICOBACTER CINAEDI AND USE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide a recombinant polypeptide (molecular weight of 30 kD) derived from Helicobacter cinaedi (H. cinaedi) and a serologically diagnostic method for H. cinaedi-infected patients using the same.;SOLUTION: Disclosed is a serologically diagnostic method comprising as a solid antigen a polypeptide having a specific amino acid sequence, the peptide characterized by (1) enabling to bind to the serum of H. cinaedi-infected patients and (2) having an amino acid sequence in which one or several amino acids are deleted, added and substituted, and a peptide comprising one part of the polypeptide. The method comprises an antigen-antibody method using any polypeptides or peptides of the peptide which can bind to the serum of H. cinaedi-infected patients. The serologically diagnostic method may be selected from the group consisting of ELISA method, Western blotting method and dot blotting method.;COPYRIGHT: (C)2009,JPO&INPIT