Antinuclear antibody and anti-CCP in the diagnosis of rheumatoid arthritis

摘要

The present invention relates to a method aiding in the assessment of rheumatoid arthritis. The method used for differential diagnosis of rheumatoid arthritis in vitro, particularly. The method, for example, carried out by analysis of biochemical markers comprises determining the concentration of both antinuclear antibodies (ANA) and anti-CCP in the sample is correlated with the diagnosis of rheumatoid arthritis measured concentration is. To further improve the assessment of RA in a method of the present invention, the level of one or more additional marker may be correlated to the absence or presence of RA is measured with ANA and anti-CCP. The present invention relates to the use of a marker panel comprising anti-CCP and ANA in the diagnosis of rheumatoid arthritis and it teaches a kit for performing the method of the present invention.