Novel pyrimidine-2,4-diamine derivatives and their use as modulators of calcium-dependent potassium channels of small conductance

摘要

This invention relates to novel pyrimidine-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.