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Improved monocyte activation test that is better able to detect non-endotoxin pyrogen contaminants in medical products
Improved monocyte activation test that is better able to detect non-endotoxin pyrogen contaminants in medical products
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机译:改进的单核细胞活化测试,能够更好地检测医疗产品中的非内毒素热原污染物
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摘要
An improved monocyte activation test is described that is better able to detect non-endotoxin pyrogens in medical products, in which a sample is incubated with a monocyte-containing reagent in an assay system comprising at least one surface comprising polypropylene. The invention also concerns assay systems for use in these tests that include at least one microtiter well having at least one interior surface comprising polypropylene and having a shape such that monocyte-containing reagent is concentrated in the well to provide greater cell to cell contact. The invention also relates to a diagnostic kit that can be used to test for the presence of non-endotoxin pyrogens in a sample.
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