To make the period of discharge and non discharge continue of the production mannered null material of cover of the medicine tablet system, and the production manner and its cup form which for discharging

摘要

Making the period of discharge and non discharge continue of the substance alternately, pharmacy activity in order to discharge the substance in the gastric fluid, the medicine tablet system which long haul floats in the gastric fluid or on the gastric fluid it is constituted from the multilayer core which is provided while covering the cup form. The core is formed, discharge layer and the non discharge layer which activity the substance is not included pharmacy continuing alternately, being piled up. As for cover of cup form, as for the surface of the core with while it exposes, it covers with the base and the side of the core. Cover of cup form obtains floatation by being formed from the compressed - sinterring blend which includes with the hydrophobic material and the inactive powder bulking agent. The hydrophobic material the fat quality which can be sinterred with compression and/or consists of the wax quality material, the bulk density is smaller than density of the gastric fluid. The powder bulking agent has characteristic is smaller than density of the gastric fluid powder density uninformed.