Within the asymmetric molecule of hydrazone 3 + 2 cycloaddition reaction method

摘要

Next formula (i)(However, R is the hydrocarbon group which is possible to have possessed the substituent)So zirconium alkoxide and next formula (ii) it is displayed(However, Y¹ and Y² each equality or difference strangely, shows the hydrogen atom or halogen atom, Y¹ and Y² as for one side shows the halogen atom at least.)So mixing the binaphthol derivative which is displayed, under existing of the asymmetrical catalytic converter system which can, it reacts the hydrazone derivative, inside the numerator of hydrazone [the 3+2] it does the cyclization addition reaction at high stereoselectivity and yield under gentle condition.