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Method for the diagnosis of small cell lung cancer, screening methods and related compositions and systems

机译:小细胞肺癌的诊断方法,筛查方法及相关组成和系统

摘要

Completely new, cancer (especially small cell lung cancer) object of the present invention to provide a technique for the diagnosis. The problems described above, the present inventors have studied intensively, in the molecular pathways of TSLC1, in particular, (in particular, (over-expressed, changes of sugar chains, such as activation) the expression levels of Rac1 and TSLC1 is, small cell lung carcinoma By found that it is closely related to the development of) and resolved. That is, a change in the activation or sugar, or altered the expression was increased relative to the step of observing the activity of Rac1, or changes in the sugar chains or increased expression of A) TSLC1, and B) and normal individuals by a method comprising the step, showing the expression of do.
机译:本发明的完全新的癌症(特别是小细胞肺癌)目的提供了一种诊断技术。如上所述的问题,本发明人对TSLC1的分子途径进行了深入研究,特别是(特别是(过表达,糖链的变化,例如活化)Rac1和TSLC1的表达水平小)。细胞肺癌被发现与它的发展密切相关并得以解决。也就是说,相对于观察Rac1活性的步骤,激活或糖的改变或表达的改变相对增加,或者A)TSLC1和B)和正常个体的糖链改变或表达增加。方法包括该步骤,显示do的表达。

著录项

  • 公开/公告号JPWO2007074832A1

    专利类型

  • 公开/公告日2009-06-04

    原文格式PDF

  • 申请/专利号JP20070551990

  • 发明设计人 村上 善則;

    申请日2006-12-26

  • 分类号C12Q1/68;C12N15/09;G01N33/574;G01N33/50;G01N33/15;

  • 国家 JP

  • 入库时间 2022-08-21 19:37:24

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