;The probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence with high intensity. Therefore, the use of the probes enables effective imaging of acidic vesicles. Further provided is a method for imaging acidic vesicles in live cells and tissue using the probes."/> Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same
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Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same

机译:用于活细胞和组织中酸性囊泡的双光子荧光探针以及使用该探针对活细胞和组织中酸性囊泡成像的方法

摘要

Provided are two-photon fluorescent probes for imaging acidic vesicles in live cells and tissue. The probes are represented by; ;The probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence with high intensity. Therefore, the use of the probes enables effective imaging of acidic vesicles. Further provided is a method for imaging acidic vesicles in live cells and tissue using the probes.
机译:提供了用于在活细胞和组织中对酸性囊泡成像的两光子荧光探针。探针由; ;这些探针可以选择性地与细胞质中的囊泡结合,从而发出高强度的双光子激发荧光。因此,使用探针能够使酸性囊泡有效成像。还提供了使用探针使活细胞和组织中的酸性囊泡成像的方法。

著录项

  • 公开/公告号US2009155837A1

    专利类型

  • 公开/公告日2009-06-18

    原文格式PDF

  • 申请/专利权人 BONG-RAE CHO;

    申请/专利号US20080288101

  • 发明设计人 BONG-RAE CHO;

    申请日2008-10-15

  • 分类号C12Q1/02;C07C233/40;

  • 国家 US

  • 入库时间 2022-08-21 19:36:28

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