METHODS FOR SOLID MUTAGENESIS AND SEMI-SOLID FLUID MUTAGENESIS FERMENTATION AND PURIFICATION OF LIPID SOLUBLE VITAMINS AND NUTRIENTS

摘要

According to the invention, Applicants have demonstrated methods for improving industrial biosynthesis of lipid soluble vitamins and nutrients. Applicants have also provided methods for cost-efficient and commercially-viable chemotherapeutic biosynthesis and purification. This invention provides novel methods for both solid mutagenesis and semi-solid fluid mutagenesis fermentation and the purification of lipid soluble vitamins and nutrients and increasing fermentation solid yields.