5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME

摘要

The present invention relates to a 5,5′-position linked 1,1′-biphenyl axis chiral ligand in chemical industry field. The present invention incorporates both the central chirality of oxazoline and the axial chirality of diphenyls. Such ligand can be used in various asymmetric reactions catalyzed by metal with high reactivity and stereoselectivity, and thus represents a good application outlook.;The ligand of the present invention has the formula of:; wherein: n=5, 6, 7, 8, 9, 10, 11 or 12; R₁=hydrogen, alkyl, substituted or unsubstituted aryl, substituted or unsubstituted benzyl; R₂=hydrogen, alkyl, substituted or unsubstituted aryl, substituted or unsubstituted benzyl; R₃=hydrogen, alkyl, substituted or unsubstituted aryl, substituted or unsubstituted benzyl; R₄=hydrogen, alkyl, substituted or unsubstituted aryl, substituted or unsubstituted benzyl.