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THERAPY FOR THE PROPHYLAXIS OR TREATMENT OF ADVERSE BODY COMPOSITION CHANGES AND/OR DECREASED MUSCLE STRENGTH AFTER ANDROGEN OR GNRH ANALOGUE INTAKE
THERAPY FOR THE PROPHYLAXIS OR TREATMENT OF ADVERSE BODY COMPOSITION CHANGES AND/OR DECREASED MUSCLE STRENGTH AFTER ANDROGEN OR GNRH ANALOGUE INTAKE
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机译:雄激素或GNRH模拟输入后不良身体组成变化和/或肌肉强度降低的预防性治疗或治疗
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摘要
Methods of treating or reducing the risk of one or more effects or signs of induced hypogonadism after androgen or GnRH intake are disclosed herein. In an embodiment, a method of treating one or more effects after androgen or gonadotropin releasing hormone (GnRH) analogue intake comprises administering to a male subject at least one of a blocking compound which antagonizes estradiol binding to estradiol receptors or an inhibitor compound which inhibits endogenous production of estradiol, after androgen or gonadotropin releasing hormone (GnRH) analogue intake, to treat the one or more effects. The one or more effects include adverse body composition changes, decreased muscle strength, or both. The inhibitor compound and/or blocking compound may include antiestrogen agents, aromatase inhibitors, or combinations thereof.
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