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COMPOSITIONS AND METHODS FOR THE REGULATION OF HOMOCYSTEINE LEVELS WITHIN THE BODY

机译:体内同型半胱氨酸水平调节的组合物和方法

摘要

Described herein is a method for reducing levels of the harmful metabolic waste product of S-adenosylmethionine (SAMe), homocysteine, and provide vitamin and other nutritional co-factors that reduce the production of homocysteine and either re-methylate homocysteine back to S-adenosylmethionine, or facilitate its conversion downstream to cystathione. The method of the invention may be achieved by administering 5-methyl tetrahydrofolate, methylcobalamin, and one or more compounds selected from the group consisting of betaine, pyridoxal-5-phosphate, N-acetyl-cysteine, and other cofactors.
机译:本文描述了一种降低S-腺苷甲硫氨酸(SAMe),高半胱氨酸的有害代谢废物产物水平并提供维生素和其他营养辅助因子的方法,所述维生素和其他营养辅因子减少了高半胱氨酸的产生并将高半胱氨酸重新甲基化为S-腺苷甲硫氨酸,或促进其向下游转化为胱硫醚。本发明的方法可以通过施用5-甲基四氢叶酸,甲基钴胺素和一种或多种选自甜菜碱,吡ido醛-5-磷酸酯,N-乙酰基半胱氨酸和其他辅因子的化合物来实现。

著录项

  • 公开/公告号US2009239826A1

    专利类型

  • 公开/公告日2009-09-24

    原文格式PDF

  • 申请/专利权人 BRIAN D. HALEVIE-GOLDMAN;

    申请/专利号US20080238586

  • 发明设计人 BRIAN D. HALEVIE-GOLDMAN;

    申请日2008-09-26

  • 分类号A61K31/675;A61P35;

  • 国家 US

  • 入库时间 2022-08-21 19:36:05

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