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PARATHYROID HORMONE TREATMENT FOR ENHANCED ALLOGRAFT AND TISSUE-ENGINEERED RECONSTRUCTION OF BONE DEFECTS
PARATHYROID HORMONE TREATMENT FOR ENHANCED ALLOGRAFT AND TISSUE-ENGINEERED RECONSTRUCTION OF BONE DEFECTS
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机译:甲状旁腺激素治疗增强异体移植和组织工程化重建骨缺损。
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摘要
Methods of improving an outcome of a bone allograft procedure in a subject suffering from a massive bone defect are described, including providing a bone allograft to the subject and intermittently providing said subject with parathyroid hormone (PTH); where the PTH is provided in an amount effective to enhance in or adjacent to a bone allograft, relative to a patient not provided the PTH, at least one of callus bone volume, callus mineral content, callus bridging, graft stiffness, graft incorporation, and graft resistance to an applied torque.
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