Method of Estimating Effect of Test Chemical on Living Organisms

摘要

A method of predicting an effect of a test chemical on living organisms, which comprises:a step of administering a plurality of chemicals whose effects on living organisms are known, to respective chemical dosed groups, administering a test chemical to a test chemical dosed group, collecting proteins from each group after a definite period of time, separating the proteins by two-dimensional gel electrophoresis, measuring the signal intensities of spots of the proteins and modified proteins formed therefrom, and calculating a signal intensity ratio of at least two spots, anda step of comparing the signal intensity ratio of test chemical dosed group with the signal intensity ratio of each chemical dosed group.