P—W—C(═X)-L-Q (I)wherein P is an optionally substituted aryl or heteroaryl group; W is an optionally substituted 6 or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 independently selected from Oxygen and Nitrogen, X is selected from Oxygen, Nitrogen and Sulphur; L is an optional C1-4 linker; and Q is an optionally substituted 4-7 membered aliphatic ring: for use in the treatment of chemokine mediated diseases or disorders."/>
Piperazine Compounds Useful as Antagonists of C-C Chemokines (Ccr2b and Ccr5) for the Treatment of Inflammatory Diseases
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Piperazine Compounds Useful as Antagonists of C-C Chemokines (Ccr2b and Ccr5) for the Treatment of Inflammatory Diseases
Piperazine Compounds Useful as Antagonists of C-C Chemokines (Ccr2b and Ccr5) for the Treatment of Inflammatory Diseases
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机译：哌嗪化合物可用作C-C趋化因子的拮抗剂（Ccr2b和Ccr5），用于治疗炎症性疾病
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摘要
A compound of formula (I); P—W—C(═X)-L-Q (I)wherein P is an optionally substituted aryl or heteroaryl group; W is an optionally substituted 6 or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 independently selected from Oxygen and Nitrogen, X is selected from Oxygen, Nitrogen and Sulphur; L is an optional C1-4 linker; and Q is an optionally substituted 4-7 membered aliphatic ring: for use in the treatment of chemokine mediated diseases or disorders.展开▼
机译：式（I）化合物; <？in-line-formulae description =“在线公式” end =“ lead”？> P-W-C（═X）-LQ（I）<？in-line-formulae description =“在线公式“ end =” tail“？> < ListItem id =“ ul0002-0001” number =“ 0000”>其中P是可选取代的芳基或杂芳基; W是任选取代的6或7元脂族环，其包含独立地选自氧和氮的环原子Y 1 和Y 2 ，X选自氧，氮和硫; L是可选的C 1-4 链接器; Q是任选取代的4-7元脂族环：用于治疗趋化因子介导的疾病或失调。
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