A3 ADENOSINE RECEPTORS AS TARGETS FOR THE MODULATION OF CENTRAL SEROTONERGIC SIGNALING

摘要

The present invention relates to the use of adenosine type 3 receptor (A3R) modulators to modulate serotonin transporter (SERT) function in vivo. In particular, antagonists of A3R can be used to inhibit A3R-dependent upregulation of SERT, for example, as antidepressants.