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PREDICTION OF BARE METAL STENT RESTENOSIS

机译:裸金属张力再塑的预测

摘要

Methods for predicting whether or not a patient is likely to experience restenosis after the placement of a bare metal stent are provided. The methods involve detecting and analyzing gene expression patterns of the cellular components of whole blood, where activation of selected genes has been found to be indicative of a high probability of restenosis. The method thus allows the identification, prior to placement of a stent, of patients who are i) likely to experience restenosis, and thus should receive a stent that includes anti-restenosis agents; or ii) unlikely to experience restenosis, and thus should receive a stent without anti-stenosis agents.
机译:提供了用于预测在放置裸金属支架之后患者是否可能经历再狭窄的方法。所述方法涉及检测和分析全血细胞成分的基因表达模式,其中发现所选基因的激活指示高再狭窄的可能性。因此,该方法允许在放置支架之前识别以下对象:i)可能经历再狭窄,因此应接受包括抗再狭窄剂的支架;或ii)不太可能发生再狭窄,因此应接受无抗狭窄剂的支架。

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