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Thermosetting Neutralized Chitosan Composition Forming a Hydrogel, Lyophilizate, and Processes for Producing the Same
Thermosetting Neutralized Chitosan Composition Forming a Hydrogel, Lyophilizate, and Processes for Producing the Same
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机译:热固性中和的壳聚糖组合物形成水凝胶,冻干粉及其制备方法
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摘要
The aqueous thermosetting neutralized chitosan composition, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C., comprises 0.1 to 5.0 w/w %, based on the total composition, of a reacetylated chitosan having a molecular weight of not smaller than 100 kDa and a deacetylation degree of 40 to 70%, neutralized with an hydroxylated base, and 1 to 30 w/w %, based on the total composition, of a complexing agent selected from polyoses and polyols derived from polyoses. Said composition is useful for the preparation of an injectable formulation.
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