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Human SLAP-2: a novel SH2/ SH3 domain-containing human SLAP homologue having immune cell-specific expression
Human SLAP-2: a novel SH2/ SH3 domain-containing human SLAP homologue having immune cell-specific expression
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机译:人SLAP-2:具有免疫细胞特异性表达的新型含SH2 / SH3域的人SLAP同源物
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摘要
The present invention describes a newly discovered full-length polynucleotide encoding an SH2/SH3 domain-containing adapter protein, called hSLAP-2, cloned, isolated and identified. Also described are the hSLAP-2 polypeptide sequence, expression vectors, host cells, agonists, antagonists, anti-sense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Methods for screening for modulators, particularly inhibitors, of the hSLAP-2 protein and use of the hSLAP-2 polynucleotide and polypeptide for therapeutics and diagnostics are described.
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