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Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds
Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds
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机译:生产5-取代的恶唑化合物和5-取代的咪唑化合物的方法
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摘要
A process for producing heterocyclic compounds which are useful as pesticides, drugs, fungicidal materials or intermediates thereof. TosMIC is reacted with an aldehyde or an imino compound: 1) in a solvent mixture of an aprotic solvent with a protic solvent in the presence of a base, 2) in the presence of a phase-transfer catalyst and an inorganic base, or 3) in the presence of an inorganic base. Thus, a desired product can be efficiently obtained using a solution without isolating TosMIC which is irritating and unstable, has a low decomposition point and shows explosivity.
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