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Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds

机译:生产5-取代的恶唑化合物和5-取代的咪唑化合物的方法

摘要

A process for producing heterocyclic compounds which are useful as pesticides, drugs, fungicidal materials or intermediates thereof. TosMIC is reacted with an aldehyde or an imino compound: 1) in a solvent mixture of an aprotic solvent with a protic solvent in the presence of a base, 2) in the presence of a phase-transfer catalyst and an inorganic base, or 3) in the presence of an inorganic base. Thus, a desired product can be efficiently obtained using a solution without isolating TosMIC which is irritating and unstable, has a low decomposition point and shows explosivity.
机译:生产用作农药,药物,杀真菌材料或其中间体的杂环化合物的方法。 TosMIC与醛或亚氨基化合物反应:1)在碱的存在下,在质子惰性溶剂与质子溶剂的溶剂混合物中,2)在相转移催化剂和无机碱的存在下,或3 )在无机碱的存在下。因此,可以使用溶液有效地获得所需产物,而无需分离刺激性和不稳定,具有低分解点并显示出爆炸性的TosMIC。

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