首页> 外国专利> Derivatives of 3-hydroxy-4-(cyclyl-alkylaminoalkyl)-5-phenyl-1h-pyrazole as antagonists of the gonadotropin releasing hormone (GnRH) for use in the treatment of sex hormone related conditions, such as prostatic of uterine cancer

Derivatives of 3-hydroxy-4-(cyclyl-alkylaminoalkyl)-5-phenyl-1h-pyrazole as antagonists of the gonadotropin releasing hormone (GnRH) for use in the treatment of sex hormone related conditions, such as prostatic of uterine cancer

机译:3-羟基-4-(环基-烷基氨基烷基)-5-苯基-1h-吡唑的衍生物,作为促性腺激素释放激素(GnRH)的拮抗剂,用于治疗与性激素有关的疾病,例如子宫癌

摘要

The invention relates to a group of novel pyrazole compounds of Formula (I): wherein: R1, R2, R3, M and R5 are as defined in the specification, which are useful as gonadotrophin releasing hormone antagonists. The invention also relates to pharmaceutical formulations of said compounds, methods of treatment using said compounds and to processes for the preparation of said compounds.
机译:本发明涉及一组式(I)的新型吡唑化合物:其中:R 1 ,R 2 ,R 3 ,M和R 5 如说明书中所定义,可用作促性腺激素释放激素拮抗剂。本发明还涉及所述化合物的药物制剂,使用所述化合物的治疗方法以及所述化合物的制备方法。

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