Metabolites isolated from oxide and N - hydroxy Derivatives of o-desmethylvenlafaxine and Treatment Methods

摘要

This provides isolated compounds characterized as metabolites or Derivatives of Hydroxy Metabolites of desmetilvenlafaxina including DV, DV - glucuronide Metabolites of Hydroxy Metabolites of N - Oxide - DV, and benzyl Hydroxy Metabolites of DV.This includes Pharmaceutical compositions comprising any of the metabolites or Derivatives of this application in combination with a pharmaceutically acceptable carrier or excipient.Also included is a method of treatment of at least a central nervous system disorder in a Mammal, comprising providing a Mammal in need thereof, an effective amount of the compounds of the present.