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butylphthalide self-emulsifying drug delivery system, its preparation and method of application

机译:邻苯二甲酸丁酯自乳化给药系统,其制备方法和应用方法

摘要

SELF-EMULSIFYING BUTYLFTALIDE MEDICINE DELIVERY SYSTEM, PREPARATION AND APPLICATION METHOD. The present invention relates to a novel drug delivery system, example: butyl phthalide self-emulsifying drug delivery system (SEMAE), for the preparation of this process and its pharmaceutical formulation. The drug delivery system comprises the essential ingredients 1% to 65% butyphataid and 10% to 65% emulsifying agent, together with various excipients as required, depending on the desired dosage form. The present invention significantly increases the contact area between butylphthalide and the mucous membrane of the gastrointestinal tract and therefore improves drug absorption.
机译:自乳化布替太利药物递送系统,制备方法及应用方法。本发明涉及用于制备该方法及其药物制剂的新型药物递送系统,例如:邻苯二甲酸丁二醇酯自乳化药物递送系统(SEMAE)。所述药物递送系统包含1%至65%的丁硫醇和10%至65%的乳化剂的基本成分以及根据需要的各种赋形剂,这取决于所需剂型。本发明显着增加了丁基邻苯二甲酸酯与胃肠道粘膜之间的接触面积,因此改善了药物吸收。

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