compound of formula (i); pharmaceutical composition; use of the compound for the treatment or control of bacterial infections in warm-blooded animals; process for the preparation of 9- (n-substituted-n-substituted-glycyl) tetracyclines of formula 5; 7; 10; and 9- (unsubstituted-n-substituted glycyl) tetracycline of formula 5; 7; 10

摘要

COMPOUND FORMULA (I); PHARMACEUTICAL COMPOSITION; USE OF THE COMPOUND FOR THE TREATMENT OR CONTROL OF BACTERIAL INFECTIONS IN HOT BLOOD ANIMALS; PROCESS FOR THE PREPARATION OF TETRACYCLINS 9- (N-SUBSTITUTED-N-SUBSTITUTED-GLYCIL) FORMULAS 5; 7; 10; And tetracycline 9- (N-substituted-N-substituted-glycyl) of formulas 5; 7; This invention provides the compounds of formula wherein: R1 is a moiety selected from the group: n is an integer of 1 or 2; R 2 is selected from hydrogen, amino, -NR 6 6 R 6 7, alkyl of 1 to 12 optionally substituted carbon atoms, aryl of 6, 10 or 14 optionally substituted carbon atoms, 2-alkenyl to 12 optionally substituted carbon atoms, 2 to 12 optionally substituted carbon alkynyl, halogen, and an optionally substituted 5-10 membered heteroaryl ring