spiro-containing compounds and compositions as modulators of steroid hormone nuclear receptors, method for the preparation of said compounds, related uses, as well as methods for modulating the activity of at least one nuclear steroid hormone receptor

摘要

COMPOUNDS AND COMPOSITIONS CONTAINING SPIRIO AS MODULATORS OF NUCLEAR STEROID HORMONE RECEPTORS, METHOD FOR PREPARING THE COMPOUND, RELATED USES, AS WELL AS METHODS FOR MODULATING THE MINIMUM NERUS RECEPTOR ACTIVITY The present invention relates to compounds having a spiro structural feature. Also described herein in this patent are methods for preparing such compounds, methods for using such compounds to modulate the activity of nuclear steroid hormone receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein in this patent application are methods for using such compounds, pharmaceutical compositions and medicaments for treating and / or preventing diseases or conditions associated with the activity of nuclear steroid hormone receptors.